Anopheles funestus - FuMOZ

Anopheles funestus

Colony Name



Anopheles funestus

Country of Origin


Liverpool Colony established (year)


Phenotypic characteristics

Resistant to pyrethroids and carbamates, susceptible to organophosphates

Source of colonisation

Originally colonised from southern Mozambique in 2000 (NICD South Africa).

Provided to LITE by Bayer Crop Science

Selection Procedur

Adults selected with 1hour exposure to 0.05% deltamethrin


Genotypic characteristics

CYP6P9a and CYP6P9b

PBO-Permethrin synergism: Significant (P < 0.001) increase in mortality (from 74% to 99%)

Note: Species I.D = SS.

Profiling Data

24 hour % mortality after 1hour exposure to Discriminating Dose


Relevant Publications

Cytochrome P450 metabolic resistance (CYP6P9a) to pyrethroids imposes a fitness cost in the major African malaria vector Anopheles funestus.Tchouakui M, Riveron Miranda J, Mugenzi LMJ, Djonabaye D, Wondji MJ, Tchoupo M, Tchapga W, Njiokou F, Wondji CS.Heredity (Edinb). 2020 May;124(5):621-632. doi: 10.1038/s41437-020-0304-1. Epub 2020 Mar 10.PMID: 32157181

Positional cloning of rp2 QTL associates the P450 genes CYP6Z1, CYP6Z3 and CYP6M7 with pyrethroid resistance in the malaria vector Anopheles funestus.Irving H, Riveron JM, Ibrahim SS, Lobo NF, Wondji CS.Heredity (Edinb). 2012 Dec;109(6):383-92. doi: 10.1038/hdy.2012.53. Epub 2012 Sep 5.

Mapping a quantitative trait locus (QTL) conferring pyrethroid resistance in the African malaria vector Anopheles funestus.Wondji CS, Morgan J, Coetzee M, Hunt RH, Steen K, Black WC 4th, Hemingway J, Ranson H.BMC Genomics. 2007 Jan 29;8:34. doi: 10.1186/1471-2164-8-34.

Pyrethroid resistance in an Anopheles funestus population from Uganda.Morgan JC, Irving H, Okedi LM, Steven A, Wondji CS.PLoS One. 2010 Jul 29;5(7):e11872. doi: 10.1371/journal.pone.0011872.