Mosquito resistance profiling and genotyping

LITE offer resistance profiling using WHO and CDC guidelines, including assessment of cross-resistance.

LITE can also assay some of the mechanisms that may underlie resistance, including PBO synergism to identify the contribution of P450 enzymes overexpression and molecular identification of the major knockdown resistance (kdr) mutations.

LITE conduct genome investigations aimed at identifying the species within the Anopheles gambiae complex which are otherwise morphologically indistinguishable.

References:

Williams et al., 2022 Insects

Williams et al., 2019 Parasit Vectors