|
Colony Name |
Cayman |
||
|
Species |
Aedes aegypti |
Country of Origin |
Grand Cayman, Caribbean |
|
Liverpool Colony established (year) |
2008 |
Phenotypic characteristics |
Resistant to DDT and pyrethroids |
|
Source of colonisation
|
MCRU, Grand Cayman (egg paper kindly provided by Dr Angela Harris)
|
Selection Procedure
|
Adults selected with 0.75 % permethrin for 1hour
|
|
Genotypic characteristics |
Kdr 1016I (0.57) Kdr 534C (0.67) Biochemical assay indicates elevated P450s and esterases Microarray/qPCR confirmed elevated P450s (CYP9 class) |
||
|
Profiling Data 24 hour % mortality after 1hour exposure to Discriminating Dose |
 |
||
|
Relevant Publications |
Bariami V, Jones CM, Poupardin R, Vontas J, Ranson H (2012) Gene Amplification, ABC Transporters and Cytochrome P450s: Unraveling the Molecular Basis of Pyrethroid Resistance in the Dengue Vector, Aedes aegypti. (link is external)PLoS Negl Trop Dis 6(6): e1692. https://doi.org/10.1371/journal.pntd.0001692 |
||