Aedes aegypti - Cayman

Aedes aegypti mosquito

Colony Name



Aedes aegypti

Country of Origin

Grand Cayman, Caribbean                    

Liverpool Colony established (year)


Phenotypic characteristics

Resistant to DDT and pyrethroids

Source of colonisation


MCRU, Grand Cayman

(egg paper kindly provided by Dr Angela Harris)


Selection Procedure


Adults selected with 0.75 % permethrin for 1hour


Genotypic characteristics

Kdr 1016I (0.57)

Kdr 534C (0.67)

Biochemical assay indicates elevated P450s and esterases

Microarray/qPCR confirmed elevated P450s (CYP9 class)

Profiling Data

24 hour % mortality after 1hour exposure to Discriminating Dose


Relevant Publications


Bariami V, Jones CM, Poupardin R, Vontas J, Ranson H (2012) Gene Amplification, ABC Transporters and Cytochrome P450s: Unraveling the Molecular Basis of Pyrethroid Resistance in the Dengue Vector, Aedes aegypti. (link is external)PLoS Negl Trop Dis 6(6): e1692.